Re: Change from 48 to 46 chromosomes

ron house (house@helios.usq.EDU.AU)
Tue, 24 Oct 1995 02:25:33 GMT (David J Betty) writes:

>48 chromosomes appear to be an ancestral state for great apes. Sometime in
>the human line of descent between the last common ancestor of humans and
>(presumably) chimps, two pairs of acrocentric chromosomes evidently fused
>to become a pair of large metacentric chromosomes. This pair are the
>second largest in humans, and examples are labelled chromosome 2. (Human
>chromosomes are labelled in approximate descending order of size.) The two
>halves of human chromosome 2 (2p and 2q) each have separate chromosomes as
>homologues in the karyotypes of chimps.

Can anyone explain how this works? I mean, if a single individual has
a mutation leaving him with a different no. of chromosomes, surely he
would not be able to breed with anyone else? Wouldn't it be impossible for
the single chromosome to match up with two separate ones?


Ron House. USQ | A nonviolent diet is the
( Toowoomba, Australia. | foundation for a nonviolent world.