Re: AAT Questions...

Elaine Morgan (
Mon, 21 Aug 1995 12:07:35 GMT


Could you please tell me more about the kind of active transport
required to excrete a substance against a gradient?

You say : "As far as I know there is not a trace of a "scar" of
such inside-outside transport in the human eccrine sweat gland."

Would I be right in thinking that one indication that this kind of
active transport was taking place would be the need to consume energy?
and an indication that such consumption of energy had taken place
after thermoregulatory sweating?

Quote from Weiner & Hellman on human thermoregulatory sweating:

"The only change, and it is a notable one, found by Shelley and Mescon
(1952) in association with glandular activity was reduction, and in
some cells, a disappearance, of glycogen - an effect inhibited by
atropine. After recovery from the effects of the heat there was a
restoration of the cellular glycogen. These changes were in fact noted
earlier by Gualdi and Baldino (1930) and by Yuyama (1935). It is clear
that glycogen depletion is closely related to glandular activity" ...

At that date (1959) no investigation of the glycogen content of eccrine
glands other than those in man had been made. If I am right in
thinking (along with Montagna) that our non-volar eccrine glands had a
different evolutionary history from those on the pads of quadrupeds and
on our own palms, there should be a distinction in this regard , as
well as in the factor which activates them (emotion versus temperature
change) between our volar and non-volar eccrine glands.

Can you tell me whether there is any difference between the two types
either in (a) degree of salt retention or (b) depletion of glycogen?